Wu Tingyao

Ingaba isetyenziswe yodwa okanye idibeneyo, i-Lingzhi (ebizwa ngokuba yi-Ganoderma lucidum okanye i-Reishi) ineempembelelo zokulawula uxinzelelo lwegazi, ukunciphisa iimpawu ezizimeleyo kunye nokuphucula i-lipids yegazi.Ngaphezu koko, ukusetyenziswa kwexesha elide kweLingzhi akuyi kubangela imiphumo emibi kwimisebenzi yomzimba.Ukuze ufumane iinkcukacha, jonga "Uvavanyo lwezonyango kwiminyaka engama-50 eyadlulayo luqinisekisile ukuba uLingzhi unokuphucula uxinzelelo lwegazi" kwaye "izifundo zeklinikhi ziqinisekisile ukuba iLingzhi iphucula uxinzelelo lwegazi kodwa ayichaphazeli uxinzelelo lwegazi oluqhelekileyo".

Nangona kunjalo, i-Lingzhi ayinayo kuphela izibonelelo ezingentla zoxinzelelo lwegazi kodwa iphucula i-viscosity yegazi, i-microcirculation (ukujikeleza kwegazi kwe-capillaries), iswekile yegazi kunye nokumelana ne-insulin kwizigulane ezinoxinzelelo lwegazi.Ngaphandle kokuchaphazela uxinzelelo lwegazi, kunokukhuthaza i-microcirculation kunye nokwandisa ukuchithwa kwegazi kubantu abaphilileyo.

I-Lingzhi iphucula uxinzelelo lwegazi kwizigulana ezinoxinzelelo lwegazi oluphezulu.

Ngowe-1992, iYunivesithi yezoNyango yaseShanghai kunye neWakan Shoyaku Laboratory Co ngokudibeneyo yapapasha ingxelo yeklinikhi kwi "Journal of Chinese Pharmaceutical Sciences", eyahlalutya inzuzo yokutya i-Lingzhi kwizigulane ezinezifo zombini ze-cardiovascular and high viscosity yegazi.Izifundo ze-33 zizonke (i-45 ukuya kwi-86 iminyaka ubudala) zavavanywa, kwaye i-17 yazo yayinoxinzelelo lwegazi.

Bathatha iipilisi ze-Lingzhi ezi-2 (ezine-110 mg ye-Lingzhi fruiting body extract, ilingana ne-2.75 g ye-Lingzhi fruiting body) ngosuku.Emva kweeveki ze-2, ngaphezu kwesiqingatha sezifundo ziphucule iimpawu zabo ezifana nentloko, i-dazzle, i-numbness yamalungu, ukuqina kwesifuba kunye nokulala;kubantu abanoxinzelelo lwegazi oluphezulu, uxinzelelo lwegazi lwe-systolic kunye ne-diastolic lwehla ngo-12.5 mmHg (8.5%) kunye ne-6.4 mmHg (7.2%), ngokulandelanayo, umehluko omkhulu wezibalo xa kuthelekiswa nangaphambi kovavanyo (Umfanekiso 1).

Uxinzelelo lwegazi lunokuchatshazelwa kukubetha kwentliziyo (inani lamaxesha entliziyo ibetha ngomzuzu xa uphumle) kwaye likwanxulunyaniswa kakuhle ne-viscosity yegazi (ukunganyangeki kwegazi).

Ekubeni zonke izifundo (kubandakanywa nezo zinexinzelelo lwegazi oluqhelekileyo) zazingenalo umehluko omkhulu kwisantya sentliziyo ngaphambi nangemva kovavanyo (amaxesha angama-74 → amaxesha angama-77), zonke zazikuluhlu oluqhelekileyo, kodwa i-viscosity yegazi yancitshiswa kakhulu.Ke ngoko, kucingelwa ukuba isizathu sokuba uLingzhi angathoba uxinzelelo lwegazi oluphezulu lunokuhambelana nokuphuculwa kwe-viscosity yegazi.

I-Lingzhi iphucula ubunzima bokunyanga uxinzelelo lwegazi kwaye iphucula i-viscosity yegazi kunye ne-microcirculation.

Ukuqinisekisa ngakumbi ukuba kukho ubudlelwane phakathi kokuphuculwa koxinzelelo lwegazi oluphezulu nguLingzhi kunye nokuphuculwa kwe-viscosity yegazi, iqela elivela kwiYunivesithi yezoNyango yaseShanghai kunye neWakan Shoyaku Laboratory Co, ngokubambisana neSibhedlele seSine sabantu baseXuzhou City, basebenzise okufanayo. Amalungiselelo Lingzhi njengoko kuphononongo ngasentla ukwenza randomized (ngamaqela), kabini-imfama (zombini abaphandi kunye nezifundo babengazi ukuba leliphi iqela izifundo babelwe) kunye novavanyo lweklinikhi elawulwa placebo kwizigulane uxinzelelo loxinzelelo lwegazi refractory.

Ngokutsho kwephepha lomphandi elipapashwe kwi-"Journal of Chinese Microcirculation" ngo-1999, "izigulane ze-hypertension eziphikisayo" ezithathe inxaxheba kuvavanyo lwezonyango zibandakanya izigulane ezinoxinzelelo olubalulekileyo olufumene unyango lwe-captopril (i-angiotensin eguqula i-enzyme inhibitor) okanye i-nimodipine (i-calcium antagonist). ) ngaphezu kwenyanga enye kodwa uxinzelelo lwegazi lwabo lusadlula i-140/90 mmHg.

Umndilili weminyaka yezifundo wawuyi-57.8 ± 9.6 iminyaka, kwaye umlinganiselo wendoda nebhinqa wawumalunga ne-2:1.Ngexesha lovavanyo, izigulana ezazithathe amayeza asentshona zathatha amayeza asentshona njengesiqhelo.Iqela le-placebo (iimeko ezili-13) zathatha indawo ye-placebo yonke imihla ngelixa iqela le-Lingzhi (iimeko ezingama-27) lathatha iipilisi ze-Lingzhi ezi-6 yonke imihla (eziqulathe i-330 mg ye-Lingzhi fruiting body extract), elingana ne-8.25 g ye-Lingzhi fruiting body;le dose yi-3 ngamaxesha ovavanyo lweklinikhi olukhankanywe ngasentla olupapashwe kwi-1992).

(1) Ukuphucuka ngokubanzi kuxinzelelo lwegazi
Emva kweenyanga ezi-3 zovavanyo, uxinzelelo lwegazi lweqela le-Lingzhi, nokuba luxinzelelo lwegazi lwe-aorta (ukulinganisa ingalo), uxinzelelo lwegazi lwe-arteriolar (ukulinganisa umnwe) okanye uxinzelelo lwegazi lwe-capillary (ukulinganisa ukugoba kwenzipho-ukugoba kwesikhumba kumda ongezantsi. umgca wesikhonkwane kunye nokugubungela ingcambu yesikhonkwane) yayiphantsi kakhulu kunangaphambi kovavanyo, kodwa akukho tshintsho lubalulekileyo kwiqela le-placebo (Umfanekiso 2).

(2)I-viscosity yegazi nayo yehla
Ngelo xesha, izibonakaliso eziphambili zokuvavanya i-viscosity yegazi, kubandakanywa izinga eliphezulu lokucheba (isantya sokuhamba kwegazi ngokukhawuleza) i-viscosity yegazi elipheleleyo, izinga eliphantsi le-shear (isantya sokuhamba kwegazi) lonke i-viscosity yegazi kunye ne-plasma viscosity echaphazela i-viscosity yegazi (igazi. i-viscosity emva kokususwa kweeseli zegazi, ezichaphazelekayo ngumxholo weprotheni, amafutha kunye neshukela legazi), yehla kakhulu kwiqela le-Lingzhi ngelixa iqela le-placebo lihlala kwindawo (Umfanekiso 3).