Umhlaza sisifo esoyikisayo esinganyangekiyo esidla amandla emzimbeni, sibangela ukwehla kobunzima bomzimba, ukudinwa ngokubanzi, ianemia kunye nokungakhululeki okwahlukeneyo.

Izigulana zomhlaza ziyaqhubeka ukuba i-polarized.Abanye abantu banokuphila nomhlaza ixesha elide, nokuba iminyaka emininzi.Abanye abantu bafa ngokukhawuleza.Siyintoni isizathu saloo mahluko?

Yintoni "ukuphila nomhlaza"?

I-etiology kunye ne-pathogenesis yomhlaza inzima.Akukho ngqiqweni ukoyisa ngokupheleleyo yonke imihlaza.Ukubetha umhlaza akufuni kubulala iiseli zomhlaza ngokupheleleyo.Ukuthintela ukukhula kunye nokusasazeka kweeseli zomhlaza kuvumela izigulane ukuba ziphile kunye neeseli zomhlaza ixesha elide, okuyindlela yokoyisa iiseli zomhlaza.Ukuphila nomhlaza kunokufezekiswa ngokudityaniswa kwamayeza emveli aseTshayina kunye namayeza aseNtshona.

Emva kokufumana unyango olujoliswe kuyo, iradiotherapy okanye ichemotherapy, uninzi lwezigulana alupheleli nje ekubeni lube buthathaka emzimbeni kodwa luba buthathaka luneempawu ezinjengobunzima bokutya, ukungasebenzi kakuhle kwamajoni omzimba, kunye nokugabha rhoqo.Kwiyeza zesiNtu zaseTshayina, ukunganyangeki kufana ne-qi ephilileyo yomzimba womntu.Ukungakhuseleki okubuthathaka kuthetha ukungonelanga kwe-qi enempilo emzimbeni, okuya kubangela izifo.

Njengoko ilizwi lihamba, iyeza lemveli laseTshayina liqinisa i-qi enempilo.Ukusetyenziswa kwamayeza emveli aseTshayina kunokunciphisa iziphumo ebezingalindelekanga zezinye iziyobisi, kuphuculwe i-tumor microenvironment, kwaye kuthintele ukukhula kwamathumba.

I-Ganoderma lucidum, eyaziwa ngokuba yi "herb magic", igugu kwindlu yobuncwane yamayeza aseTshayina, kwaye umsebenzi wayo oyintloko kukuqinisa i-qi enempilo.

Izifundiswa zaseMelika zeGanoderma: Iyonke iTriterpenesukusuka I-Ganoderma lucidumzineempawu ezichasene nethumba.

Ngo-2008,Ijenali yaMazwe ngaMazwe yeSayensi zeMolekyuliutyhile ukuba uphando lwamva nje lwesazinzulu saseMelika uGqr Daniel Sliva lufumanise ukubaI-Ganoderma lucidumiyonke i-triterpenoids (eyaziwa njengeI-Ganoderma lucidumi-spore oil) ine-anti-tumor kunye ne-anti-inflammatory properties.

Ngokusekelwe kwisigqibo sophando lweI-Ganoderma lucidumi-triterpenoids eyenziwe nguGqr Daniel Sliva, inqaku libonisa ukuba i-triterpenoids iyonke yeI-Ganoderma lucidumequlathe i-ganoderic acid F inokunciphisa i-tumor angiogenesis in vitro ngelixa i-ganoderic acid X inokwenza i-extracellular signal-regulated kinases kunye ne-dual-specificity kinases, ngaloo ndlela ibangele i-apoptosis yeseli ye-tumor kunye nokukhuthaza ukufa kweeseli zethumba lesibindi somntu.Ijenali yaMazwe ngaMazwe yeSayensi zeMolekyuli ekugqibeleni ubonisa uGqr Daniel Sliva kwisigqibo sophando:I-Ganoderma lucidum, yendalo "I-Ganoderma lucidumtriterpenes”, inokuphuhliswa ibe yinto entsha ngokusetyenziswa kwe-anti-tumor.(Fujian Agriculture, INkupho 2, 2012, iphepha 33-33)

Iziko loPhando loMhlaza laseIndiya: I-Ganoderma lucidumI-triterpenes inokuthintela ngokufanelekileyo ukusinda kweeseli zomhlaza.

IZiko loPhando loMhlaza lase-Amala lipapashe ingxelo kwiUPhando lweNguqungoJanuwari 2017, ebonisa ukubaI-Ganoderma lucidumI-triterpenes inokuthintela ngokufanelekileyo ukusinda kweeseli zomhlaza kunye nokunciphisa ukwenzeka kunye nobukhulu bamathumba nokuba zisetyenziswe ngaphandle okanye ngaphakathi.

Izinto zovavanyo ezisetyenzisiweyo kolu phononongo yi-triterpene iyonke isicatshulwa somzimba weziqhamoI-Ganoderma lucidum.Isiphumo sokuhlakulela isicatshulwa esipheleleyo se-triterpene kunye neseli yomhlaza webele womntu i-MCF-7 (exhomekeke kwi-estrogen) kukuba okukhona kugxininisekile kwisicatshulwa, ixesha elide lisebenza kwiiseli zomhlaza, kwaye ngakumbi kunokunciphisa izinga lokusinda. yeeseli zomhlaza.Kwezinye iimeko, inokwenza iiseli zomhlaza zinyamalale (kumfanekiso ongezantsi).

Uvavanyo ngakumbi lwafumanisa ukuba isizathu sokubaI-Ganoderma luciduminokuthintela ukukhula kweeseli zomhlaza ayisiyiyo "ngobundlobongela", kodwa "ngokufakwa" ukulawula ijene kunye neemolekyuli zeprotheyini kwiiseli zomhlaza, ukucima ukutshintshela ukwanda kweeseli zomhlaza, kwaye uqalise i-apoptosis yeeseli zomhlaza.

(Wu Tingyao,I-Ganoderma, IZiko loPhando loMhlaza laseIndiya liqinisekisile ukubaI-Ganoderma lucidumi-triterpenoids inokunciphisa umngcipheko womhlaza)

Zhibin Lin:I-Ganoderma lucidumisetyenziswa kakhulu kwi-adjuvant chemotherapy kunye ne-radiotherapyumhlaza.

UNjingalwazi uZhibin Lin wasePeking University Health Science Centre, oye wafundaI-Ganodermangaphezu kweminyaka engama-50, ekhankanywe kwincwadi ethi “Thetha malungaI-Ganoderma” ukuba inani elikhulu lezifundo zeklinikhi kunye nezenzo zeziyobisi zibonakalise okoI-Ganoderma luciduminokomeleza ukhuselo lomzimba lokulwa nethumba, iphucule isiphumo sokunyanga amayeza echemotherapy, inciphise ityhefu kunye neziphumo ebezingalindelekanga ezifana ne-leukopenia, ukulahleka kweenwele, ukuphelelwa ngumdla wokutya, isicaphucaphu, ukuhlanza, urhudo, ukwehla kobunzima, ukonakala kwesibindi kunye nezintso okubangelwa yiradiotherapy kunye unyango lwemichiza, kunye nokuphucula ukunyamezela abaguli abanomhlaza kwi-chemotherapy, ukuphucula umgangatho wobomi bezigulana ezinomhlaza kunye nokwandisa ubomi babo.Nangona inani elincinci lezigulana eziphulukene nethuba le-radiotherapy kunye ne-chemotherapy ziye zafumana iziphumo zokunyangaI-Ganoderma lucidumwedwa,I-Ganoderma lucidumisetyenziswa rhoqo ukuncedisana nechemotherapy kunye neradiotherapy.

Ukususela kumbono wemigaqo ye-TCM yonyango "yokomeleza i-qi enempilo kunye nokuphelisa izinto ze-pathogenic", i-chemotherapy kunye ne-radiotherapy kuphela ingqalelo "ukuphelisa izinto ze-pathogenic" kunye nokungahoywa "ukomeleza i-qi enempilo", kunye nokonakalisa i-qi enempilo.Indima yeI-Ganoderma lucidumkwi-chemotherapy yomhlaza kunye ne-radiotherapy yenza nje ukusilela kwezi zonyango zimbini, oko kukuthi, ngokwenene "yomeleza i-qi ephilileyo kwaye isuse izinto ezibangela izifo".I-multi-component kunye ne-multi-target anti-tumor effect yeI-Ganoderma lucidum, kunye nendima yayo ekukhuseleni ukulimala okubangelwa yi-radiotherapy kunye ne-chemotherapy, ukuchazwa kwanamhlanje kwesiphumo "sokuqinisa i-qi enempilo kunye nokuphelisa izinto ze-pathogenic".

(Ekuqaleni ipapashwe kwi "Ganoderma", 2011, Issue 51, amaphepha 2 ~ 3)

Ukuphila nomhlaza ayilonyango lokwenziwa, singasathethi ke ngokuyeka unyango.Igxininisa imeko "yokuhlalisana ngoxolo" nomhlaza.Ukugcina "ithemba + unyango" lunokukwazi ukufezekisa ixesha elide lokuphila nomhlaza.