Gumiguru 2017 / Dicle University / Korean Journal yeNeurotrauma

Chinyorwa/ Wu Tingyao

Kare zvainzwika kuti vamwe vanhu vakakuvara muuropi nekuda kwetsaona.Mukuwedzera pakurapwa nguva dzose, vakatorawo zvakawandaGanoderma lucidum.Nekuda kweizvozvo, kukurumidza uye mhedzisiro yekupora zvaive zvisingatarisirwi.Nyaya yechi63 (Spring 2014) ye "Healthy Ganoderma" yakabudiswa neMicrobiology Culture and Education Foundation yakaunzawo nyaya nhanhatu dzekushandisa.Ganoderma lucidumkudzosera kumashure kukuvadzwa kunokonzerwa netsaona dzemotokari.

Is Ganoderma lucidumsaka "mashiripiti"?Chirevo chakabudiswa mu "Korean Journal of Neurotrauma" (South Korean Journal of Neurotrauma) neDicle University muTurkey muna Gumiguru 2017 yakasimbisa kuburikidza nekuedza kwemhuka kuti iyo polysaccharide yakatorwaGanoderma lucidumMitumbi inobereka michero inogona chaizvo kukurumidza kudzoreredza kukuvadzwa kwehuropi, uye maitiro ayo ekuita ane hukama nekudzikisa oxidative kusagadzikana uye kudzikamisa kuzvimba.

Vatsvakurudzi vakashandisa nzira yekugadzira "kudonha kubva pakakwirira" kukonzera kukuvara kwehuropi mumakonzo.Hafu yavo (16 rats) havana kugamuchira chero kurapwa (brain trauma group).Imwe hafu (brain trauma +Ganoderma lucidumgroup) akadyiswa neGanoderma lucidum pachiyero chezuva nezuva che20 mL pakirogiramu yehuremu hwemuviri maminitsi makumi matatu mushure mekurwadziwa (mL imwe neimwe yeGanoderma lucidummvura inotorwa ine 2 mg ye polysaccharides).Kushungurudzika kwehuropi hwemakonzo kunoongororwa mushure memazuva manomwe.Kuedza kwakashandisawo makonzo (control group) nemakonzo akajairwa akadyiswa nawoGanoderma lucidumpolysaccharide(Ganoderma lucidumgroup) kuenzanisa nemapoka maviri apfuura.

Kubuda ropa muuropi kunogona kukonzera kuzvimba, kuwedzera oxidative pressure muuropi (antioxidant enzymes ichaderera, uye huwandu hwemahara radicals huchawedzera), uye zvinogona kukonzera edema (iyo inosvina uropi tishu uye kuikuvadza).Iyo yepakutanga yeropa-brain barriers (yakasikwa chipingamupinyi pakati petsinga dzeropa nehuropi chinogona kuvharira zvinhu zvekunze kuti zvipinde muuropi) zvichaparadzwa zvakare, zvichikonzera kuti mamwe masero machena eropa apinde muuropi kana kukonzera hutachiona hwehuropi, zvichiita kuti kuzvimba kuwedzere. .

Aya mamiriro haakodzeri kudzoreredza kwehuropi tishu kubva mukushungurudzika.Asi maererano nemigumisiro yekuedza kwemhuka mumushumo uyu, mushure mokunge makonzo akakuvadzwa muuropi akarapwaGanoderma lucidumpolysaccharide kwemazuva manomwe, huropi hwavo hushoma kukuvadzwa nemahara radicals (MDA inoderedza), iyo antioxidant enzyme GSH iyo inoderedza mahara radicals muuropi inowedzera, chena masero eropa kuzvimba kunenge kushoma (kuburitswa kweperoxidase MPO kushoma), cerebral. edema inovandudzwawo zvakanyanya, uye kupera kweropa-brain barriers iri pedyowo neyakajairwa- ese maitiro akasiyana zvakanyanya neaya europi-akakuvadzwa makonzo asina kuwana chero kurapwa (ona tafura iri pasi apa).

Mukuwedzera, inogona kuonekwa kubva muzvikamu zvemuviri zvecerebral cortex izvoGanoderma lucidumpolysaccharides inogona kuvandudza tsinga yeropa uye edema, kugadzirisa masero etsinga, uye kukurumidza kupora kwehuropi hwakakuvara (sezvinoratidzwa pazasi).The cerebral cortex inoreva chimiro chakabatana-seganda chine makwinya mazhinji akaputirwa nekunze kwehuropi.Inoita basa rekunzwa kwepamusoro-soro uye kugona kufunga.Naizvozvo, kudzoreredzwa kwenzvimbo iyi kunokosha zvikuru.

Vatsvakurudzi vakaedzawo zvimwe zvitatu zvakakosha zviratidzo muhutano hwegonzo, kusanganisira protein kinase p38 MAPK, iyo inonyatsoenderana nekuputika, vascular endothelial growth factor (VEGF), iyo inofanirwa kugadzirisa vascular structure, uye microglial cell, iyo inokonzera kubvisa masero etsinga akakuvadzwa uye zvirwere.

Zvakaonekwa kuti, zvichienzaniswa nemakonzo akakuvadzwa neuropi asina kudyaGanoderma lucidumpolysaccharides, kunyangwe basa reP38 MAPK rakanga richiri kuonekwa mumakonzo akakuvadzwa muuropi aidya.Ganoderma lucidumpolysaccharides, (inoratidza kuti kuita kwaienderera mberi asi kwakange kwakadzorwa uye kwaisazonyanya kuipa), vascular endothelial growth factor uye microglial cell yakawedzera zvakanyanya, zvichiratidza kutiGanoderma lucidumpolysaccharide inobatsira pakugadzirisa uye kuvakazve midziyo yeuropi uye cranial nerves.

Migumisiro yekuedza iri pamusoro inoratidza kushanda kwekuenderera mberi kwehutungamiri hweGanoderma lucidumpolysaccharides kwemazuva manomwe mushure mekukuvadzwa kweuropi.Vatsvakurudzi vanotenda kuti kana chiyero chakakodzera cheGanoderma lucidumma polysaccharides anogona kushandiswa se adjuvant therapy mushure mekukuvadzwa kwehuropi, zvichabatsira zvakanyanya mukuderedza kuzvimba uye cerebral edema, kana kudzivirira masero etsinga uye glial masero.

[Kwakabva] Özevren H, et al.Ganoderma Lucidum inodzivirira rat brain tissue kurwisa trauma-induced oxidative stress.Korean J Neurotrauma.2017;13(2): 76-84.

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Nezve munyori/ Ms. Wu Tingyao

Wu Tingyao anga achitaura nezvekutanga-ruokoGanoderma lucidumruzivo kubvira 1999. Ndiye munyori weKuporesa neGanoderma(yakabudiswa muThe People's Medical Publishing House muna Kubvumbi 2017).
 
★ Chinyorwa ichi chakatsikiswa pasi pemvumo yakasarudzika yemunyori

★ Mabhuku ari pamusoro haagone kutsikiswa, kutorwa kana kushandiswa nedzimwe nzira pasina mvumo yemunyori

★ Kutyorwa kwechirevo chiri pamusoro, munyori achaita mabasa ayo ane chekuita nemutemo

★ Manyoro ekutanga echinyorwa ichi akanyorwa neChinese naWu Tingyao uye akashandurirwa muchiRungu naAlfred Liu.Kana paine mutsauko pakati peshanduro (yeChirungu) neyekutanga (Chinese), iyo yekutanga Chinese ichakunda.Kana vaverengi vaine mibvunzo, tapota taura nemunyori wemabviro, Ms. Wu Tingyao.