Kodi Lingzhi ali ndi choletsa pa buku la coronavirus (SARS-CoV-2)?Kodi kudya Lingzhi mutadwala chibayo cha coronary (COVID-19) kumathandizira kupondereza coronavirus yatsopano?

Takhala tikugwiritsa ntchito ntchito ya "Ganoderma lucidum's immune regulation" monga maziko a chiphunzitso cha "anti-virus ya Ganoderma lucidum".Tsopano, pamapeto pake pali umboni wachindunji wotipatsa ife yankho lomveka bwino.

Lipoti lofalitsidwa ndi gulu la kafukufuku waku Taiwan ku PNAS (Proceedings of the National Academy of Sciences) pa Januware 15 chaka chino (2021) lidatsimikizira kuti Ganoderma lucidum polysaccharides, imodzi mwazinthu zomwe zimagwira ntchito mu Ganoderma lucidum, imatha kuletsa matenda a cell ndi buku la coronavirus, limaletsa kubwereza ndi kuchuluka kwa buku la coronavirus m'maselo, ndikuchepetsa kuchuluka kwa kachilombo ka corona m'mapapo nyama zitatenga kachilombo ka coronavirus.

Imaletsa kuchulukitsa kwa ma virus popanda kuwononga ma cell

Gulu lofufuza lomwe latchulidwa pamwambapa lidachita zoyeserera mu vitro: choyamba, ma cell a Vero E6 ndi chotsitsa cha Ganoderma lucidum polysaccharide (dzina la code RF3) adakulitsidwa pamodzi, kenako buku la coronavirus lidawonjezedwa kuti liwone kuchuluka kwa kubwezeredwa kwa ma virus ndi kupulumuka kwa ma cell pambuyo pake. maola 48.

Monga tonse tikudziwa, buku la coronavirus limalowa m'thupi la munthu kudzera pa cholandilira cha ACE2 paselo.Maselo a Vero E6 ochokera ku impso za anyani obiriwira aku Africa amatha kuwonetsa kuchuluka kwa ma ACE2 receptors, chifukwa chake akakumana ndi buku la coronavirus, buku la coronavirus limatha kulowa mosavuta m'maselowa kuti abwereze ndikuchulukirachulukira.

Zotsatira zikuwonetsa kuti kutulutsa kwa Ganoderma lucidum polysaccharide kumatha kuchepetsa kuchuluka kwa kachilomboka mpaka theka pamlingo wochepa wa 2 μg/mL popanda kuchititsa kufa kwa cell (onani chithunzi ndi zolemba zomwe zatengedwa mu lipoti la kafukufuku pansipa kuti mumve zambiri).

Gwero/PNAS February 2,2021 118(5) e2021579118

Chepetsani kuchuluka kwa kachilomboka m'mapapo a hamster

Chotsatira chinali kuyesa kwa nyama: ma hamster adayamba kudwala kachilombo ka corona, kenako Ganoderma lucidum polysaccharide extract idaperekedwa kwa ma hamster awa pakamwa pa mlingo watsiku ndi tsiku wa 200 mg/kg kwa masiku atatu.

Zinapezeka kuti kuchuluka kwa kachilombo m'mapapo a hamster kunali pafupifupi theka la gulu lolamulira (popanda mankhwala aliwonse) (monga momwe tawonetsera pa chithunzi pansipa), ndipo kulemera kwa hamster sikunagwere kwambiri.Izi zikutanthauza kuti chotsitsa cha Ganoderma lucidum polysaccharide sichingalepheretse kuchulukira kwa buku la coronavirus komanso ndichotetezeka kwambiri kudya.

Gwero/PNAS February 2, 2021 118(5)e2021579118

Gwero/PNAS February 2,2021 118(5)e2021579118

Musachepetse zotsatira za kuyesa kwa "hamster".Minofu yopuma ya hamster ndi yofanana ndi ya anthu.Chitetezo cha mthupi chikalimbikitsidwa ndi matenda, minofu yopuma ya hamster imakhalanso ndi ma cytokines otupa ofanana ndi anthu.Chifukwa chake, zotsatira za Reishi bowa polysaccharide Tingafinye ndi buku la coronavirus kumenyana wina ndi mzake pa hamsters ndizofunika kwambiri.

Reishi polysaccharides amasiyana ndi mankhwala opitilira 3,000 ndi zowonjezera

Zoyeserera pamwambapa zatiwonetsa kuti Ganoderma lucidum polysaccharides imatha kuteteza maselo ndikulimbana ndi matenda atsopano a coronavirus - osachepera akatengedwa matenda asanatengedwe kapena panthawi yoyamba ya matenda, Ganoderma lucidum polysaccharides amakhala ndi antivayirasi wabwino kwambiri.

Sizophweka kuti Ganoderma lucidum polysaccharides akhoza kuonekera mu kafukufukuyu.

Gulu lofufuzalo lidatenga koyamba mankhwala a anthu kapena anyama okwana 2,855 ovomerezedwa ndi US Food and Drug Administration (FDA).Chachiwiri, gululo lidasankha mankhwala pafupifupi 200 okhala ndi machiritso a matenda obwera chifukwa cha ma virus kuchokera ku mankhwala azitsamba achi China.Kenaka, gululo linayang'ana mankhwala 15 kapena zosakaniza zomwe zingathe kulimbana ndi matenda opatsirana pogwiritsa ntchito ma cell omwe amayesedwa mu labotale ya P3.

Gululo lidawina mankhwala 7 apamwamba kwambiri kapena zosakaniza pazoyeserera zanyama kuti zigwirizane ndi zovuta za kachilomboka.Pamapeto pake, mitundu iwiri yokha yamankhwala (mankhwala oletsa malungo otchedwa mefloquine ndi mankhwala oletsa matenda a Edzi otchedwa neflinavir) ndi mitundu itatu yamankhwala azitsamba ndi zotulutsa zamasamba (Reishi bowa polysaccharides, Perilla frutescens ndi Mentha haplocalyx) zomwe zimatha kugwiritsa ntchito antiviral. zotsatira m'thupi.

Pakati pa zinthu zisanu izi, Ganoderma lucidum polysaccharides yokha imatha kukhala yothandiza polimbana ndi ma virus popanda kuchititsa kufa kwa maselo, kuchepa thupi kapena kukhudza magwiridwe antchito a thupi.

Kuphatikiza apo, ma polysaccharides ndi amodzi mwazinthu zomwe zimagwira ntchito mu Ganoderma lucidum.Ngati titha kuwonjezera ma triterpenes kapena kugwiritsa ntchito Ganoderma lucidum yonse kulimbana ndi kachilomboka, chidzachitika ndi chiyani?

Katemera amatha kuteteza gawo limodzi la thupi lathu, koma ndi chiyani chomwe chiyenera kugwiritsidwa ntchito kuteteza mbali yomwe katemera sangathe kuiteteza?

Tiyeni tidye bowa wambiri wa Reishi!

Ndipo ayenera kukhala bowa wa Reishi yemwe adalimidwa mokhazikika, kuchotsa, ndi kukonza, ali ndi zosakaniza zonse ndipo ali ndi kuvomereza kwazakudya.Bowa wa Reishi okhawo sangakukhumudwitseni.

【Chitsime cha data】

Jia-Tsrong Jan, et al.Kuzindikiritsa mankhwala omwe alipo komanso mankhwala azitsamba ngati zoletsa matenda a SARS-CoV-2.PNAS February 2, 2021 118 (5) e2021579118;

https://doi.org/10.1073/pnas.2021579118.

TSIRIZA

Za wolemba/ Mayi Wu TingyaoWu

Tingyao wakhala akufotokoza za chidziwitso choyamba cha Ganoderma lucidum kuyambira 1999. Iye ndi mlembi wa "Ganoderma lucidum: Ingenious Beyond Description" (yofalitsidwa mu The People's Medical Publishing House mu April 2017).

★ Nkhaniyi yasindikizidwa pansi pa chilolezo cha wolemba, ndipo umwini wake ndi wa GANOHERB

★ Ntchito zomwe zili pamwambazi sizingapangidwenso, kuchotsedwa kapena kugwiritsidwa ntchito mwanjira ina popanda chilolezo cha GanoHerb.

★ Ngati ntchitozo zaloledwa kugwiritsidwa ntchito, ziyenera kugwiritsidwa ntchito molingana ndi chilolezo ndikuwonetsa gwero: GanoHerb

★ Kuphwanya mawu omwe ali pamwambawa, GanoHerb idzatsatira maudindo ake okhudzana ndi malamulo

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