Julayi 2, 2016 / Xiangya Hospital Central South University, njll / International Journal of Biological Macromolecules
Umbhalo / Wu Tingyao

Abanye odokotela bake basebenzisa “iphedi lokukhuhla” ukuchaza ukubukeka kwamaphaphu ane-fibrotic.Ngalesi sikhathi, i-alveoli ilahlekelwe umsebenzi wokushintshanisa umoya, okuthinta kakhulu ukuphefumula.Imbalwa imithi ethize yokwelapha.Izinga lokusinda leminyaka emihlanu leziguli ezine-pulmonary fibrosis liphansi kuneleziguli ezinomdlavuza wamaphaphu.Ngakho-ke, ngaphandle uma i-pulmonary fibrosis itholakala ekuqaleni, okungukuthi, lapho udonga lwe-alveolar luvutha, kunethuba elingcono lokuvimbela noma ukubambezela ukuwohloka kwesifo.Uma isifinyelele esigabeni se-tissue fibrosis, ukwelashwa kuba nzima kakhulu.Ukuphazamiseka kokuphefumula kusenesikhathi, ukuphelelwa umoya nokukhwehlela okomile kuvame ukushaywe indiva iziguli noma ukuxilonga odokotela.Ngakho-ke, lapho iziguli eziningi zitholakala ukuthi zine-pulmonary fibrosis, zingene ezigabeni ezimaphakathi nezakamuva zalesi sifo.

Ukubhema, i-reflux ye-gastroesophageal, amathonya emvelo, izakhi zofuzo, ukuguqulwa kwezakhi zofuzo, izidakamizwa nezinye izici kungase kubangele ukulimala kwamaphaphu nokuvuvukala ngokweqile isikhathi eside, okuholela ekuveleni kwe-pulmonary fibrosis.Nokho, uma amaphaphu angavikelwa ngeI-Ganoderma lucidumngesikhathi esifanayo, inkinga ye-pulmonary fibrosis ingase ixazululwe.

Ucwaningo olwenziwa uMnyango Wezokwelapha Zokuphefumula, i-Xiangya Hospital Central South University, ngokubambisana namayunithi amaningi, luqinisekisile ukuthi ama-polysaccharides avela.I-Ganoderma lucidum(PGL) ingavimbela futhi yelaphe i-pulmonary fibrosis ebangelwa umuthi wokulwa nomdlavuza i-bleomycin.Lo mphumela ushicilelwe ku-International Journal of Biological Macromolecules ngoJulayi 2016.