July 2, 2016 / Xiangya Hospital Central South University, etc. / International Journal of Biological Macromolecules
Zolemba / Wu Tingyao

Madokotala ena nthawi ina amagwiritsa ntchito mawu akuti "scouring pad" pofotokoza mawonekedwe a mapapu a fibrotic.Panthawiyi, alveoli yataya ntchito yosinthanitsa mpweya, zomwe zimakhudza kwambiri kupuma.Pali mankhwala ochepa ochizira.Kupulumuka kwazaka zisanu kwa odwala omwe ali ndi pulmonary fibrosis ndi otsika kuposa odwala khansa ya m'mapapo.Choncho, pokhapokha ngati pulmonary fibrosis imapezeka kumayambiriro, ndiko kuti, pamene khoma la alveolar lapsa, pali mwayi wabwino wopewa kapena kuchedwetsa kuwonongeka kwa matendawa.Akafika pa siteji ya minofu fibrosis, mankhwala ndi zovuta kwambiri.Matenda a kupuma koyambirira, kupuma movutikira komanso chifuwa chowuma nthawi zambiri amanyalanyazidwa ndi odwala kapena osadziwika bwino ndi madokotala.Choncho, odwala ambiri akapezeka ndi pulmonary fibrosis, alowa pakati ndi mochedwa magawo a matendawa.

Kusuta, gastroesophageal reflux, chilengedwe, majini, kusintha kwa majini, mankhwala osokoneza bongo ndi zinthu zina zingayambitse kuwonongeka kwa mapapo ndi kutupa kwakukulu kwa nthawi yaitali, zomwe zimapangitsa kuti pakhale pulmonary fibrosis.Komabe, ngati mapapu akhoza kutetezedwa ndiGanoderma lucidumnthawi yomweyo, vuto la pulmonary fibrosis likhoza kuthetsedwa.

Kafukufuku wopangidwa ndi dipatimenti ya Respiratory Medicine, Xiangya Hospital Central South University, mogwirizana ndi mayunitsi angapo, adatsimikizira kuti ma polysaccharides ochokeraGanoderma lucidum(PGL) imatha kuteteza ndi kuchiza pulmonary fibrosis yoyambitsidwa ndi mankhwala oletsa khansa a bleomycin.Zotsatirazi zidasindikizidwa mu International Journal of Biological Macromolecules mu Julayi 2016.