Juni 23, 2011 / Kobe Pharmaceutical University / Phytotherapy Research

Umbhalo/ Wu Tingyao

Ukuvaleka kwamakhala, ikhala elilumayo, ukuthimula kanye nekhala eligijimayo kuyizimpawu ezivamile ze-“allergic rhinitis”, futhi impova ingenye yezifo ezibangelwa ukungezwani komzimba ne-rhinitis.Phakathi nenkathi yokuqhakaza, othile uyazijabulela izimbali, kodwa othile uzonda ikhala lakhe.Mhlawumbe ukudlaI-Ganoderma lucidumngesineke kungenza ikhala eliguliswayo lingabi nokungezwani komzimba.

Umbiko wocwaningo oshicilelwe uMnyango Wezesayensi Yezokwelapha wase-Kobe Pharmaceutical University e-Japan kokuthi "Phytotherapy Research" ngo-2011 wasebenzisa ama-guinea pigs njengezifundo zokuhlola.Abacwaningi baqale benza izingulube ze-Guinea zihogela impova kakhulu phakathi nesonto ukuze zenze umzimba ongezwani.Ngemva kwekhefu lesonto, benza ama-guinea pig ahogele impova kanye ngosuku ukuze abangele ukungezwani nekhala.Futhi, ezinsukwini ezimbili ngaphambi kokuthi izingulube ze-Guinea "zihogele impova", abacwaningi baqala ukuphakela izingulube.I-Ganoderma lucidumImpushana yomzimba enezithelo (Iqukethe u-7.5% we-chitin no-40%I-Ganoderma lucidumpolysaccharide) ngethamo lika-100 noma i-1,000 mg ngekhilogremu yesisindo somzimba ngosuku amasonto ayisishiyagalombili.

Kwatholakala ukuthi uma kuqhathaniswa nezingulube ze-Guinea ezazingavikelweI-Ganoderma lucidum, iqembu lamagwinya elalinawoI-Ganoderma lucidumbase benciphise kakhulu izimpawu zabo zokuminyana emakhaleni kusukela ngesonto lesihlanu (umthamo omkhulu uholela emiphumeleni engcono);inani lokuthimula nalo lancipha (umphumela wemithamo ephansi ufana nowomthamo omkhulu).

Ngisho noma abacwaningi basebenzisa i-leukotriene (omunye wabaxhumanisi bokuvuvukala okubangela ukungezwani komzimba) ukuze bandise ukucasuka esigabeni sakamuva sokuhlolwa, iqembu elidle umthamo ophezulu.I-Ganoderma lucidumwayethinteke kancane ekuphefumuleni kwekhala.

Ukuhlola kuphinde kwathola ukuthi ngemva kokuyeka ukusetshenziswa kweI-Ganoderma lucidum, uma izingulube ze-Guinea zivezwa ngokuqhubekayo ezinto ezingezwani nomzimba, umphumela weI-Ganoderma lucidumekwehliseni ukuminyana emakhaleni kusekhona evikini lokuqala, kodwa ngeviki lesibili, isimo sokuminyana emakhaleni siba sibi kakhulu njengesalezo ngulube ezingadlanga.I-Ganoderma lucidum.

Ngaphezu kwalokho, ukuthathaI-Ganoderma lucidumisikhathi esifushane asisebenzi, ngoba abacwaningi baye bazama ukondla izingulube ze-Guinea ngezimpawu ze-rhinitis inyanga eyodwa nesigamu ngomthamo omkhulu we-Ganoderma ngesonto, kodwaI-Ganodermalucidumayikwazanga ukuthuthukisa ukuminyana kwamakhala ezingulube ze-Guinea.

Lolu cwaningo lusikhumbuza lokhoI-Ganoderma lucidumingathuthukisa i-rhinitis ye-allergic, kodwa ukuthuthukiswa okunjalo akukwazi ukwenziwa ngobusuku obubodwa.I-Ganoderma lucidumizobonisa imiphumela yayo lapho ithathwa isikhathi esithile futhi iqhubeke nokusebenza lapho ithathwa ngaphandle kokuphazamiseka.Kulesi sivivinyo, "akuzange" kuphawulwe lokhoI-Ganoderma lucidumkunganciphisa inani le-IgE, okubonisa lokhoI-Ganoderma lucidumkunomphumela osobala "wokuvimbela ukuvuvukala" ekuthuthukiseni izimpawu ze-allergies esigabeni sokuqala.Kungase kuthathe isikhathi esiningi ukulungisa ukuqina komzimbaI-Ganoderma lucidum, futhi kungcono ukuhlala kude ne-allergener.

Ngokuqondene nokuthi kungani abacwaningi bekhetha izingulube ze-Guinea ukuze bazihlole?Ngenxa yokuthi abaphefumuli ngemilomo yabo, ukunemba kwemiphumela yokuhlola kuthuthukiswa kakhulu.

[Umthombo] Mizutani N, et al.Umthelela we-Ganoderma lucidum ekuvinjweni kwekhala okubangelwa impova ku-guinea pig model ye-rhinitis engezwani ne-allergic.I-Phytother Res.2012 Mar;26(3):325-32.doi: 10.1002/ptr.3557.Epub 2011 Jun 23.

PHELA

Mayelana nombhali/ Nks. Wu Tingyao

U-Wu Tingyao ubelokhu ebika mathuphaI-Ganoderma lucidumulwazi kusukela ngo-1999. Ungumbhali weUkwelapha nge-Ganoderma(ishicilelwe ku-People's Medical Publishing House ngo-Ephreli 2017).

★ Lesi sihloko sishicilelwe ngaphansi kwegunya elikhethekile lombhali ★ Le misebenzi engenhla ayikwazi ukuphinda ikhiqizwe, icashunwe noma isetshenziswe ngezinye izindlela ngaphandle kwemvume yombhali ★ Ukwephulwa kwesitatimende esingenhla, umbhali uzoqhuba izibopho zayo zomthetho ezihlobene ★ Eyokuqala umbhalo walesi sihloko ubhalwe ngesiShayina nguWu Tingyao futhi wahunyushelwa esiNgisini ngu-Alfred Liu.Uma kukhona ukungqubuzana phakathi kokuhumusha (isiNgisi) kanye nokwangempela (isiShayina), isiShayina sangempela siyonqoba.Uma abafundi benemibuzo, sicela uthinte umbhali wokuqala, uNksz. Wu Tingyao.