Musangano weInternational Medicinal Mushroom (IMMC) ndechimwe chezviitiko zvakakura zvakanyanya muindasitiri yehowa yepasi rose inodyiwa uye yemishonga.Nechiyero chayo chepamusoro, hunyanzvi uye kudyidzana nedzimwe nyika, inozivikanwa se "Olympics yeindasitiri yehowa inodyika uye yemishonga".

Musangano uyu inzvimbo yekuti vesainzi vanobva kunyika, matunhu nezvizvarwa zvakasiyana-siyana vadzidze pamusoro pebudiriro itsva uye nzira itsva dzehowa hunodyika uye hwemishonga.Icho chiitiko chikuru mumunda wehowa hunodyiwa uye hwemishonga munyika.Kubva pakaitwa musangano wekutanga weInternational Medicinal Mushroom muKyiv, guta guru reUkraine muna 2001, musangano uyu wave uchiitwa makore maviri ega ega.

Kubva munaGunyana 27 kusvika 30th, iyo 11th International Medicinal Mushroom Conference yakaitirwa muCrowne Plaza Belgrade, guta guru reSerbia.Sebhizimusi rinotungamira muChina organic Reishi indasitiri uye chete mutsigiri wepamba, GanoHerb yakakokwa kutora chikamu muchiitiko ichi.

Chiitiko che11th International Medicinal Mushroom Conference

Musangano uyu wakarongwa neInternational Society for Medicinal Mushrooms uye University of Belgrade uye inorongwa pamwe chete neFaculty of Agriculture- Belgrade, Institute for Biological Research "Siniša Stanković", iyo Mycological Society yeSerbia, iyo European Hygienic Engineering & Dhizaini Boka, iyo Faculty yeBiology-Belgrade, iyo Faculty yeSainzi-Novi Inosiririsa, iyo Faculty of Natural Science-Kragujevac uye Faculty yeFarmacy-Belgrade.Yakakwezva mazana enyanzvi uye masayendisiti munharaunda inodyiwa uye yekurapa howa kubva kuChina, North America, Europe neSerbia.

Dingindira remusangano uyu rinoti “Medicinal Mushroom Science: Innovation, Challenges and Perspectives”, ine mishumo yakakosha, masemina akakosha, zviratidziro zvemaposta, uye kuratidzwa kweindasitiri yehowa hunodyika uye hwemishonga.Musangano unotora mazuva mana.Vamiriri vakaungana kuti vataure nekukurukura nyaya dzichangoburwa uye dzakakosha dzedzidzo mundima yehowa hunodyika uye hwemishonga.

Musi wa28 Gunyana, Dr. Ahmed Attia Ahmed Abdelmoaty, akarimwa pamwe chete neGanoHerb Postdoctoral Research Station uye Fujian Medical University, akagovera "Senolytic effect ye triterpenoids complex NT yakatorwa kubvaGanoderma lucidumpamasero ekenza yechiropa” online.

Kenza yechiropa ibundu rinouraya rinowanzoitika.Cellular senescence chiratidzo chitsva cheCancer chakabatanidzwa mubutiro rekuongorora kwepamusoro magazini Cancer Discovery muna Ndira gore rino (Cancer Discov. 2022; 12: 31-46).Inobata basa rakakosha mukudzoka uye chemotherapy kuramba kenza kusanganisira kenza yechiropa.

Ganoderma lucidum, inozivikanwa se "magic herb" muChina, inonyanyozivikanwa yemishonga fungus uye tsika dzechiChinese mushonga.Inowanzoshandiswa kudzivirira nekurapa hepatitis, zvirwere zvekudzivirira zvirwere uye kenza.Mishonga inoshandiswa yeGanoderma lucidum inonyanya kuita triterpenoids uye polysaccharides, iyo ine mishonga yemishonga yehepatoprotection, antioxidation, antitumor, immune regulation uye antiangiogenesis.Nekudaro, pakave pasina mushumo wemabhuku nezve senolytic mhedzisiro yeGanoderma lucidum pane senescent cancer maseru.

Vachitungamirwa naProfessor Jianhua Xu, director weFujian Provincial Key Laboratory yePharmacology of Natural Medicine, Chikoro cheFarmacy, Fujian Medical University, vaongorori veGanoHerb Postdoctoral Research Station vakashandisa chemotherapeutic drug doxorubicin (ADR) kukurudzira kenza yechiropa. ndokuzorapwa neGanoderma lucidumtriterpenoid yakaoma NT kuti iongorore mhedzisiro yayo pakutaura kwesenescence marker mamorekuru emasero ecancer echiropa, chikamu chemasero emasero, apoptosis uye autophagy yemaseru maseru uye senescence-yakabatana secretory phenotype (SASP).

Chidzidzo ichi chakawana kuti Ganoderma lucidum triterpenoid yakaoma NT inogona kuderedza chikamu chesescent cancer cancer maseru uye kukonzeresa apoptosis ye senescent cancer cancer maseru.Inogona kubvisa maseru ekenza yechiropa uye inhibit SASP mumasero emukenza wechiropa nekudzivisa NF-κB, TFEB, P38, ERK uye mTOR nzira dzechiratidzo, kunyanya kuvharidzirwa kweIL-6, IL-1β uye IL-1α.

Ganoderma lucidumtriterpenoid complex NT inogona kunyatso kuvharidzira kukurudzira kwemasero emukenza wechiropa pakupararira kwemasero ekenza yechiropa akapoteredzwa nekubvisa masero ekenza yechiropa uye anogonawo kuwirirana ne-anti-hepatocellular carcinoma effect ye sorafenib.Izvi zvakawanikwa zvine kukosha kukuru uye tarisiro ingangove yekudzidza kwemishonga mitsva yeantitumor yakavakirwa pane anti-cellular senescence.

Nzvimbo yekuratidzira yemusangano

GanoHerb inopa nyanzvi uye nyanzvi pasi rese nezvinwiwa zvakaita seReishikofi.