Ihuriro mpuzamahanga ry’ubuvuzi bw’ibihumyo (IMMC) ni kimwe mu bintu byagize uruhare runini mu nganda ziribwa n’imiti ku isi.Hamwe n’ibipimo bihanitse, ubunyamwuga n’amahanga, bizwi nka “Olempike yinganda ziribwa n’imiti”.

Iyi nama ni urubuga rwabahanga baturutse mubihugu bitandukanye, uturere ndetse nibisekuru kugirango bige kubyagezweho nuburyo bushya bwibihumyo biribwa nubuvuzi.Nibikorwa bikomeye mubijyanye nibihumyo biribwa nubuvuzi kwisi.Kuva inama mpuzamahanga ya mbere y’ubuvuzi bw’ibihumyo yaberaga i Kyiv, umurwa mukuru wa Ukraine mu 2001, iyi nama iba buri myaka ibiri.

Kuva ku ya 27 kugeza ku ya 30 Nzeri, Inama mpuzamahanga ya 11 y’imiti y’ibihumyo yabereye i Crowne Plaza Belgrade, umurwa mukuru wa Seribiya.Nkumushinga wambere mu nganda nganda za Reishi nu Bushinwa n’umuterankunga umwe rukumbi mu gihugu, GanoHerb yatumiwe kwitabira ibi birori.

Amashusho yinama mpuzamahanga ya 11 yubuvuzi bwibihumyo

Iyi nama yateguwe n’umuryango mpuzamahanga w’ubuvuzi bw’ibihumyo na kaminuza ya Belgrade ikaba yateguwe n’ishami ry’ubuhinzi- Belgrade, Ikigo cy’ubushakashatsi ku binyabuzima “Siniša Stanković”, Sosiyete Mycologiya yo muri Seribiya, Uburayi bw’Ubwubatsi bw’Uburayi & Itsinda Ryashushanyije, Ishami rya Biologiya-Belgrade, Ishami rya siyansi-Novi Sad, ishami rya siyansi y’ubumenyi-Kragujevac n’ishami rya Farumasi-Belgrade.Yashimishije abanyamwuga n’abahanga babarirwa mu magana mu bushakashatsi bw’ibiribwa biribwa n’imiti biva mu Bushinwa, Amerika y'Amajyaruguru, Uburayi na Seribiya.

Insanganyamatsiko y'iyi nama ni “Ubuvuzi bwa Mushroom Science: Guhanga udushya, imbogamizi n'ibitekerezo”, hamwe na raporo nyamukuru, amahugurwa adasanzwe, kwerekana ibyapa, hamwe n’imurikagurisha ry’ibihingwa by’ibihumyo biribwa kandi bivura.Ihuriro rimara iminsi 4.Abahagarariye bateraniye hamwe kugira ngo batange raporo kandi baganire ku bibazo bigezweho kandi by'ingenzi bijyanye n'amasomo mu bijyanye n'ibihumyo biribwa n'imiti.

Ku ya 28 Nzeri, Dr. Ahmed Attia Ahmed Abdelmoaty, wahinzwe hamwe na GanoHerb Postdoctoral Research Station na kaminuza y’ubuvuzi ya Fujian, yasangiye “Ingaruka za Senolitike y’ikigo cya triterpenoide NT yakuwe muriGanoderma lucidumkuri kanseri y'umwijima ya senescent "kumurongo.

Kanseri y'umwijima ni ikibyimba kibi.Senescence ya selile ni ikimenyetso gishya cya Kanseri yashyizwe mu isubiramo ry'ikinyamakuru cyo hejuru Kanseri Discovery muri Mutarama uyu mwaka (Kanseri Discov. 2022; 12: 31-46).Ifite uruhare runini mugusubiramo no kuvura imiti ya kanseri harimo na kanseri y'umwijima.

Ganoderma lucidum, izwi ku izina rya “herb magic” mu Bushinwa, ni ibihumyo bizwi cyane bivura imiti n'ubuvuzi gakondo bw'Abashinwa.Bikunze gukoreshwa mu gukumira no kuvura hepatite, indwara z'umubiri na kanseri.Ibintu bifatika bya Ganoderma lucidum ni triterpenoide na polysaccharide, bifite ibikorwa bya farumasi bya hepatoprotection, antioxyde, antitumor, kugenzura immunite na antiangiogenez.Nyamara, nta raporo y’ubuvanganzo yigeze ivuga ku ngaruka za senolitike ya Ganoderma lucidum ku ngirabuzimafatizo za kanseri.

Bayobowe na Porofeseri Jianhua Xu, umuyobozi wa Laboratoire y’Intara ya Fujian y’Ubuvuzi bwa Farumasi y’Ubuvuzi Kamere, Ishuri rya Farumasi, Kaminuza y’Ubuvuzi ya Fujian, abashakashatsi bo mu kigo cy’ubushakashatsi cya Postoctoral GanoHerb bakoresheje imiti ya chimiotherapeutique doxorubicin (ADR) kugira ngo batera kanseri y’umwijima. hanyuma hanyuma akavurwa hamweGanoderma lucidumtriterpenoid complex NT kugirango isesengure ingaruka zayo kumagambo ya molekile ya senescence ya selile ya kanseri yumwijima, igipimo cya selile senescent, apoptose na autophagy ya selile senescent hamwe na fenotype yibanga ya senescence (SASP).

Ubushakashatsi bwerekanye ko Ganoderma lucidum triterpenoid complex NT ishobora kugabanya igipimo cya kanseri yumwijima ya senescent kandi igatera apoptose ya kanseri yumwijima.Irashobora gukuraho selile ya kanseri yumwijima kandi ikabuza SASP mungirangingo ya kanseri yumwijima ya senescent ihagarika NF-κB, TFEB, P38, ERK na mTOR yerekana inzira, cyane cyane kubuza IL-6, IL-1β na IL-1α.

Ganoderma lucidumtriterpenoid complex NT irashobora guhagarika neza ingaruka ziterwa ningirabuzimafatizo ya kanseri yumwijima ya senescent ku ikwirakwizwa rya kanseri y’umwijima ikikije kanseri y’umwijima kandi ishobora no guhuza n'ingaruka zo kurwanya kanseri ya hepatocellular ya sorafenib.Ibyavuye mu bushakashatsi bifite akamaro gakomeye kandi birashoboka ko byiga ku miti mishya ya antitumor ishingiye kuri senescence anti-selile.

Agace k'imurikagurisha

GanoHerb itanga abahanga nintiti kwisi yose ibinyobwa nkaReishiikawa.