Machende ndiwo poyambira ubwamuna, ndipo umuna ndiwo ankhondo pankhondo.Kuvulala kumbali zonse kungakhudze chonde.Komabe, pali zinthu zambiri m'moyo monga coronavirus yatsopano yomwe ili yovulaza ma test ndi umuna.Kodi machende ndi umuna zingatetezedwe bwanji?

Mu 2021, gulu la Mohammad Nabiuni, pulofesa wothandizira wa Dipatimenti ya Ma Cellular ndi Molecular Biology, Kharazmi University, Iran, adafalitsa kafukufuku mu Tissue and Cell, ponena kuti ethanol Tingafinye kuchokera ku fruiting body ya Ganoderma lucidum ikhoza kuteteza ma testes ndi ma testes. umuna wa nyama.

Pogwiritsa ntchito lithiamu carbonate, mankhwala achipatala a mania, monga chinthu chovulaza, ochita kafukufuku anadyetsa mbewa zathanzi 30 mg / kg ya lithiamu carbonate (gulu la lithiamu carbonate) tsiku ndi tsiku, komanso kudyetsa mbewa zina zathanzi 75 mg / kg. Ganoderma lucidum ethanol extract (ochepa mlingo wa Reishi + lithium carbonate gulu) tsiku lililonse kapena 100 mg/kg ya Ganoderma lucidum ethanol extract (mkulu wa Reishi + lithium carbonate gulu) tsiku lililonse.Ndipo adafanizira ma testis a gulu lililonse la mbewa patatha masiku 35.

Ganoderma lucidum imateteza mphamvu ya spermatogenesis ya machende.

95% ya kuchuluka kwa ma testis omwe ali mu scrotum amakhala ndi "machubu otulutsa umuna", timagulu tating'ono tating'ono tating'ono tating'ono tating'ono tating'ono tating'ono tating'ono tating'ono tating'ono tating'ono tating'ono tating'ono tating'ono tating'ono tating'ono tating'ono tating'ono tating'ono tating'ono tating'ono tating'ono tating'ono tating'ono tating'ono tating'ono tating'ono tating'ono tating'ono tating'ono tating'ono tating'ono tating'ono tating'ono tating'ono tating'ono tating'ono tating'ono tating'ono tating'ono tating'ono tating'ono ta machubu omwe amatchedwanso "seminiferous tubules".

Zomwe zili bwino ziyenera kukhala monga momwe zilili m'munsimu.Lumen ya seminiferous tubules idzadzazidwa ndi umuna wokhwima, ndipo "spermogenic epithelium" yomwe imapanga khoma la chubu ili ndi "maselo a spermogenic" pazigawo zosiyanasiyana za chitukuko.Pakati pa seminiferous tubules, pali "interstitial minofu ya testis".Testosterone yotulutsidwa ndi maselo a minofu iyi (ma cell interstitial) sikuti imangothandiza kugonana komanso imapanga malo omwe amachititsa kuti umuna uyambe kukula.

Minofu ya testicular ya mbewa zathanzi mu kafukufukuyu idawonetsa mphamvu zamphamvu zomwe zatchulidwa pamwambapa.Mosiyana ndi zimenezi, minofu ya machende ya mbewa mu gulu la lithiamu carbonate inasonyeza kufota kwa seminiferous epithelium, kufa kwa spermatogonia, umuna wokhwima wocheperako m’machubu a seminiferous, ndi kuchepa kwa minyewa yapakati pa machende.Komabe, zinthu zomvetsa chisoni zoterezi sizinachitike kwa mbewa zomwe zili mu gulu la lithiamu carbonate lotetezedwa ndi Ganoderma lucidum.
Minofu ya testicular ya "mkulu wa Reishi + lithium carbonate gulu" inali pafupifupi yofanana ndi ya mbewa zathanzi.Sikuti epithelium ya seminiferous inali yokha, komanso machubu a seminiferous anali odzaza ndi umuna wokhwima.

Ngakhale machubu a seminiferous a "mlingo wochepa wa Reishi + lithiamu carbonate gulu" amawonetsa kufooka pang'ono kapena kuchepa pang'ono, machubu ambiri a seminiferous anali akadali amphamvu kuchokera ku spermatogonia kupita ku umuna wokhwima (spermatogonia → spermatocytes oyambirira → spermatocyte yachiwiri → spermatids) .

Kuonjezera apo, mawu a pro-apoptotic jini BAX, yomwe imasonyeza apoptosis, mu minofu ya testis ya mbewa inawonjezekanso kwambiri chifukwa cha kuwonongeka kwa okosijeni komwe kumachitika chifukwa cha lithiamu carbonate, koma kuwonjezeka kumeneku kungathenso kuthetsedwa ndi kumwa mosalekeza kwa Ganoderma. lucidum.

Ganoderma lucidum imathandiza kusunga umuna ndi khalidwe.

Ofufuzawo adasanthulanso kuchuluka ndi mtundu (kupulumuka, kuyenda, kusambira) kwa umuna wa mbewa.Ubwamuna apa umachokera ku "epididymis" pakati pa testis ndi vas deferens.Ubwamuna ukapangidwa mu machende, umakankhidwa apa kuti upitirire kukula kukhala umuna wokhala ndi kuyenda kwenikweni komanso mphamvu ya umuna kudikirira kutulutsa.Choncho, malo osauka epididymal adzakhala zovuta kuti umuna kusonyeza mphamvu zawo.

Chithunzi chomwe chili pansipa chikuwonetsa kuti lithiamu carbonate imayambitsa kuwonongeka kwa okosijeni kwa epididymal minofu ndikuchepetsa kuchuluka kwa umuna, kupulumuka, kuyenda komanso kusambira.Koma ngati pali chitetezo ku Ganoderma lucidum nthawi yomweyo, mlingo wa kuchepetsa umuna ndi kufowoka adzakhala ochepa kwambiri kapena osakhudzidwa kwathunthu.

Chinsinsi cha Ganoderma lucidum kuteteza umuna wa amuna chagona mu "antioxidation".

The ethanolic Tingafinye wa Ganoderma lucidum fruiting matupi ntchito kuyesera munali polyphenols (20.9 mg/mL), triterpenoids (0.0058 mg/mL), polysaccharides (0.08 mg/mL), okwana antioxidant ntchito kapena kutha mbwebwe DPPH ufulu ankafuna kusintha zinthu mopitirira (88.86) %).Ntchito yabwino kwambiri imeneyi ya antioxidant imatengedwa ndi ochita kafukufuku kuti ndi chimodzi mwa zifukwa zazikulu za Ganoderma lucidum ethanol Tingafinye kuteteza testicular ndi epididymal zimakhala ndi kusunga spermatogenesis ndi umuna motility.

M'moyo weniweni, nthawi zambiri timamva kuti amayi osabereka a nthawi yayitali amatenga mimba atatenga Ganoderma lucidum kwa nthawi, zomwe zikutanthauza kuti Ganoderma lucidum akhoza kuchita chinachake kwa chiberekero cha amayi, mazira kapena endocrine system;tsopano kafukufukuyu akuwonetsa kuti Ganoderma lucidum ikhoza kupindulitsanso njira zoberekera za amuna.

Mothandizidwa ndi Ganoderma lucidum, ngati banja likuyesera kubereka ana awo, ndithudi adzalandira kawiri zotsatira ndi theka la khama.Ngati saganizira za chonde koma amangofuna chisangalalo chogwirizana, kuwala kwa chikondi mothandizidwa ndi Ganoderma lucidum kuyenera kukhala kokongola kwambiri.

[Zindikirani] Mtengo wa P wa gulu la lithiamu carbonate mu matchati umachokera ku kuyerekeza ndi gulu lathanzi, ndipo mtengo wa P wa magulu awiri a Ganoderma lucidum umachokera ku kuyerekeza ndi gulu la lithiamu carbonate, * P <0.05, ** * P <0.001.Mtengo wocheperako, umasiyananso kwambiri.

Buku
Ghazal Ghajari, et al.Kuyanjana pakati pa poizoni wa testicular wopangidwa ndi Li2Co3 ndi chitetezo cha Ganoderma lucidum: Kusintha kwa Bax & c-Kit genes expression.Tissue Cell.2021 Oct;72:101552.doi: 10.1016/j.tice.2021.101552.

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