Mgbakọ ero ọgwụ mba ụwa (IMMC) bụ otu n'ime nnukwu ihe omume kachasị emetụta na ụlọ ọrụ ero nri na ọgwụ zuru ụwa ọnụ.Site na ọkọlọtọ ya dị elu, ọkachamara na mba ụwa, a maara ya dị ka "Olympic nke ụlọ oriri na ọṅụṅụ na-agwọ ọrịa ero".

Nzukọ a bụ ikpo okwu maka ndị ọkà mmụta sayensị si mba dị iche iche, mpaghara na ọgbọ dị iche iche iji mụta banyere mmezu ọhụrụ na ụzọ ọhụrụ nke ero nri na ọgwụ.Ọ bụ nnukwu mmemme n'ọhịa nke ero nri na ọgwụ n'ụwa.Ebe ọ bụ na e mere ọgbakọ Mushroom mbụ nke mba ụwa na Kyiv, isi obodo Ukraine na 2001, a na-enwe ogbako ahụ kwa afọ abụọ.

Site na Septemba 27th ruo 30th, e mere ọgbakọ 11th International Medicinal Mushroom Conference na Crowne Plaza Belgrade, isi obodo Serbia.Dị ka ụlọ ọrụ na-eduga na ụlọ ọrụ organic Reishi nke China na naanị onye nkwado ụlọ, GanoHerb kpọrọ oku isonye na mmemme a.

Ebe ogbako ero ogwu mba uwa nke iri na otu

Ọ bụ International Society for Medicinal Mushrooms na Mahadum Belgrade haziri nzukọ a na ngalaba ngalaba nke Agriculture- Belgrade, Institute for Biological Research “Siniša Stanković”, Mycological Society of Serbia, European Hygienic Engineering & Design Group, ngalaba nke Biology-Belgrade, ngalaba nke Sayensị-Novi Sad, ngalaba nke Natural Science-Kragujevac na ngalaba nke Pharmacy-Belgrade.Ọ dọtara ọtụtụ narị ndị ọkachamara na ndị ọkà mmụta sayensị na mpaghara nyocha ero nri na ọgwụ sitere na China, North America, Europe na Serbia.

Isiokwu nke ogbako a bụ "Sayensị ero ọgwụ: Innovation, Challenges and Perspections", nwere akụkọ isi okwu, nzukọ ọmụmụ pụrụ iche, ihe ngosi akwụkwọ mmado, na ihe ngosi ụlọ ọrụ ihe oriri na ọgwụ.Nzukọ a na-ewe ụbọchị anọ.Ndị nnọchi anya ahụ gbakọtara ka ha kọọ ma kparịta ihe gbasara agụmakwụkwọ kachasị ọhụrụ na nke bụ isi n'ihe gbasara ero nri na ọgwụ.

Na Septemba 28th, Dr. Ahmed Attia Ahmed Abdelmoaty, bụ ndị GanoHerb Postdoctoral Research Station na Fujian Medical University zụlitere, kesara “Senolytic mmetụta nke triterpenoids complex NT ewepụtara na ya.Ganoderma lucidumna mkpụrụ ndụ cancer imeju nke anụ ahụ" online.

Ọrịa cancer imeju bụ akpụ akpụ a na-ahụkarị.Senescence cellular bụ akara ọhụrụ nke Ọrịa Cancer gụnyere na nyocha mkpuchi nke akwụkwọ akụkọ kachasị elu Cancer Discovery na Jenụwarị afọ a (Cancer Discover. 2022; 12: 31-46).Ọ na-arụ ọrụ dị mkpa na nlọghachi azụ na ọgwụgwọ chemotherapy nke ọrịa cancer gụnyere ọrịa imeju.

Ganoderma lucidum, nke a maara dị ka "osisi anwansi" na China, bụ ero ọgwụ a ma ama na ọgwụ ọdịnala ndị China.A na-ejikarị ya egbochi ma na-agwọ ịba ọcha n'anya, ọrịa na-alụso ọrịa ọgụ na ọrịa kansa.Ogige ndị na-arụ ọrụ nke Ganoderma lucidum bụ triterpenoids na polysaccharides, nke nwere ọrụ ọgwụ nke hepatoprotection, antioxidation, antitumor, usoro mgbochi na antiangiogenesis.Agbanyeghị, enwebeghị akwụkwọ akụkọ gbasara mmetụta senolytic nke Ganoderma lucidum na mkpụrụ ndụ kansa.

N'okpuru nduzi nke Prọfesọ Jianhua Xu, onye nduzi nke Fujian Provincial Key Laboratory of Pharmacology of Natural Medicine, School of Pharmacy, Fujian Medical University, na-eme nchọpụta na GanoHerb Postdoctoral Research Station jiri chemotherapeutic ọgwụ doxorubicin (ADR) mee ka imeju mkpụrụ ndụ cancer cancer. wee mesoo yaGanoderma lucidumtriterpenoid complex NT iji nyochaa mmetụta ya na ngosipụta nke mkpụrụ ndụ ihe nrịbama nke senescence nke mkpụrụ ndụ cancer imeju nke anụ ahụ, oke nke mkpụrụ ndụ senescent, apoptosis na autophagy nke mkpụrụ ndụ senescent na senescence-metụtara secretory phenotype (SASP).

Nnyocha ahụ chọpụtara na Ganoderma lucidum triterpenoid complex NT nwere ike ibelata ọnụ ọgụgụ nke mkpụrụ ndụ cancer imeju nke anụ ahụ ma mee ka apoptosis nke mkpụrụ ndụ cancer imeju ume.Ọ nwere ike iwepụ mkpụrụ ndụ cancer imeju nke anụ ahụ ma gbochie SASP na mkpụrụ ndụ cancer imeju nke anụ ahụ site na igbochi NF-κB, TFEB, P38, ERK na mTOR ụzọ mgbaàmà, karịsịa mgbochi nke IL-6, IL-1β na IL-1a.

Ganoderma lucidumtriterpenoid complex NT nwere ike igbochi mmetụta na-akwalite nke mkpụrụ ndụ cancer imeju na mmụba nke mkpụrụ ndụ cancer imeju gbara ya gburugburu site na iwepụ mkpụrụ ndụ cancer imeju nke anụ ahụ ma nwee ike imekọrịta na mmetụta mgbochi hepatocellular carcinoma nke sorafenib.Nchọpụta ndị a nwere nnukwu uru na atụmanya ndị nwere ike ime maka ọmụmụ ọgwụ ọhụrụ antitumor dabere na senescence mgbochi cell.

Mpaghara ngosi ogbako

GanoHerb na-enye ndị ọkachamara na ndị ọkà mmụta gburugburu ụwa ihe ọṅụṅụ dị kaReishikọfị.