Lub Rooj Sib Tham Thoob Ntiaj Teb Kev Kho Mob Mushroom (IMMC) yog ib qho ntawm cov xwm txheej loj tshaj plaws hauv kev lag luam nceb noj thiab tshuaj ntsuab.Nrog nws cov txheej txheem siab, kev tshaj lij thiab kev ua haujlwm thoob ntiaj teb, nws yog lub npe hu ua "Olympics of the edible and medicinal mushroom industry".

Lub rooj sib tham yog lub platform rau cov kws tshawb fawb los ntawm ntau lub teb chaws, cheeb tsam thiab ntau tiam neeg los kawm txog kev ua tiav tshiab thiab cov txheej txheem tshiab ntawm cov nceb noj thiab tshuaj.Nws yog ib qho kev tshwm sim loj nyob rau hauv lub tshav pob ntawm edible thiab tshuaj nceb nyob rau hauv lub ntiaj teb no.Txij li thawj thawj lub rooj sib tham International Medicinal Mushroom tau muaj nyob rau hauv Kyiv, lub peev ntawm Ukraine nyob rau hauv 2001, lub rooj sib tham tau tuav txhua ob xyoos.

Txij lub Cuaj Hlis 27th txog rau 30th, 11th International Medicinal Mushroom Conference tau muaj nyob rau hauv Crowne Plaza Belgrade, lub peev ntawm Serbia.Raws li lub tuam txhab ua lag luam hauv Tuam Tshoj cov organic Reishi kev lag luam thiab tsuas yog tus neeg txhawb nqa hauv tsev, GanoHerb tau raug caw tuaj koom rau hauv qhov kev tshwm sim no.

Qhov chaw ntawm 11th International Medicinal Mushroom Conference

Lub rooj sib tham yog tsim los ntawm International Society for Medicinal Mushrooms thiab University of Belgrade thiab koom tes los ntawm Kws Qhia Ntawv ntawm Kev Ua Liaj Ua Teb- Belgrade, Lub Tsev Haujlwm rau Kev Tshawb Fawb Txog Kev Tshawb Fawb "Siniša Stanković", Mycological Society of Serbia, European Hygienic Engineering & Pawg tsim, Kws qhia ntawv ntawm Biology-Belgrade, Kws qhia ntawv ntawm Science-Novi Sad, Kws qhia ntawv ntawm Natural Science-Kragujevac thiab Kws Qhia Ntawv ntawm Pharmacy-Belgrade.Nws nyiam ntau pua tus kws tshaj lij thiab cov kws tshawb fawb hauv kev tshawb fawb txog nceb thiab tshuaj ntsuab los ntawm Tuam Tshoj, North America, Europe thiab Serbia.

Lub ntsiab lus ntawm lub rooj sib tham no yog "Medicinal Mushroom Science: Innovation, Challenges and Perspectives", nrog rau cov lus ceeb toom tseem ceeb, cov rooj sib tham tshwj xeeb, cov ntawv nthuav qhia, thiab cov khoom noj khoom haus thiab tshuaj ntsuab kev lag luam nthuav qhia.Lub rooj sab laj kav ntev li 4 hnub.Cov neeg sawv cev tau sib sau ua ke los tshaj tawm thiab sib tham txog qhov tseeb thiab cov teeb meem kev kawm tseem ceeb hauv kev noj cov nceb thiab tshuaj ntsuab.

Thaum lub Cuaj Hlis 28th, Dr. Ahmed Attia Ahmed Abdelmoaty, uas tau koom ua ke cog qoob loo los ntawm GanoHerb Postdoctoral Research Station thiab Fujian Medical University, tau qhia txog "Senolytic nyhuv ntawm triterpenoids complex NT rho tawm los ntawmGanoderma lucidumntawm senescent daim siab mob hlwb "online.

Mob qog noj ntshav yog ib hom qog nqaij hlav malignant.Cellular senescence yog lub cim tshiab ntawm Cancer muaj nyob rau hauv daim npog tshuaj xyuas ntawm cov ntawv xov xwm sab saum toj Cancer Discovery nyob rau lub Ib Hlis xyoo no (Cancer Discov. 2022; 12: 31-46).Nws ua lub luag haujlwm tseem ceeb hauv kev rov tshwm sim dua thiab kho tshuaj kho mob ntawm cov qog nqaij hlav nrog rau daim siab mob qog noj ntshav.

Ganoderma lucidum, hu ua "magic tshuaj ntsuab" nyob rau hauv Suav teb, yog ib tug paub zoo tshuaj fungus thiab tsoos suav tshuaj.Nws yog feem ntau siv los tiv thaiv thiab kho kab mob siab, kab mob tiv thaiv kab mob thiab mob qog noj ntshav.Cov tshuaj nquag ntawm Ganoderma lucidum feem ntau yog triterpenoids thiab polysaccharides, uas muaj cov tshuaj ua haujlwm ntawm hepatoprotection, antioxidation, antitumor, kev tiv thaiv kab mob thiab antiangiogenesis.Txawm li cas los xij, tsis muaj ntaub ntawv qhia txog cov nyhuv senolytic ntawm Ganoderma lucidum ntawm cov qog nqaij hlav senescent.

Raws li kev taw qhia ntawm xibfwb Jianhua Xu, tus thawj coj ntawm Fujian Provincial Key Laboratory ntawm Pharmacology ntawm Natural Medicine, Tsev Kawm Ntawv ntawm Pharmacy, Fujian Medical University, cov kws tshawb fawb ntawm GanoHerb Postdoctoral Research Station tau siv cov tshuaj chemotherapeutic doxorubicin (ADR) los ua rau mob qog noj ntshav cell senescence. thiab ces kho nrogGanoderma lucidumtriterpenoid complex NT los txheeb xyuas nws cov teebmeem ntawm kev qhia ntawm senescence marker molecules ntawm senescent daim siab mob qog noj ntshav, qhov kev faib ua feem ntawm senescent hlwb, apoptosis thiab autophagy ntawm senescent hlwb thiab senescence-associated secretory phenotype (SASP).

Txoj kev tshawb nrhiav pom tias Ganoderma lucidum triterpenoid complex NT tuaj yeem txo qhov kev faib ua feem ntawm lub siab mob qog noj ntshav thiab ua rau apoptosis ntawm senescent daim siab mob hlwb.Nws tuaj yeem tshem tawm cov kab mob qog nqaij hlav hauv siab thiab inhibit SASP hauv senescent daim siab mob hlwb los ntawm inhibiting NF-κB, TFEB, P38, ERK thiab mTOR signaling pathways, tshwj xeeb tshaj yog inhibition ntawm IL-6, IL-1β thiab IL-1α.

Ganoderma lucidumtriterpenoid complex NT tuaj yeem cuam tshuam qhov kev txhawb nqa ntawm senescent daim siab mob qog noj ntshav ntawm kev loj hlob ntawm ib puag ncig lub siab mob qog noj ntshav los ntawm kev tshem tawm senescent daim siab qog nqaij hlav hlwb thiab tuaj yeem ua ke nrog cov tshuaj tiv thaiv hepatocellular carcinoma ntawm sorafenib.Cov kev tshawb pom no muaj qhov tseem ceeb thiab muaj peev xwm ua tau zoo rau kev kawm txog cov tshuaj antitumor tshiab raws li kev tiv thaiv cellular senescence.

Exhibition cheeb tsam

GanoHerb muab cov kws tshaj lij thiab cov kws tshawb fawb thoob ntiaj teb nrog cov dej haus xws liReishikas fes.