(Kumu: CNKI)

ʻO ka poʻe makemake i ka kofe e hōʻoluʻolu iā lākou iho i kēlā me kēia lā, hopohopo lākou no ka inu ʻana i ka nui o ka kofe.Inā inu ʻoe i ka kofe Reishi, hiki iā ʻoe ke pale i kēlā mau hopohopo a loaʻa i kahi ʻohi i manaʻo ʻole ʻia.

Wahi a kahi hōʻike noiʻi i paʻi ʻia maʻEpekema Meaʻai a me ʻenehanama 2017 e ka National and Local Joint Engineering Research Center no ka mahiʻai ʻana a me ka hoʻoponopono hohonu ʻana o nā fungi lāʻau lapaʻau, ʻo ka kofe Reishi ka hopena o ka hoʻonui ʻana i ka palekana.

ʻO kaKofe Reishihoʻohana ʻia i kēia noiʻi he hui kūpono oʻO Ganoderma lucidumka ʻai a me ka kofe, hāʻawi ʻia e GanoHerb Technology (Fujian) Corporation.ʻO nā holoholona hoʻokolohua he ʻiole ICR, i hoʻohana nui ʻia i ka lāʻau lapaʻau, toxicology, tumor, meaʻai a me nā noiʻi ʻepekema ʻē aʻe.

ʻEkolu mau ʻano ʻokoʻa (1.75, 3.50 a me 10.5 g/kg, ʻo ia hoʻi 5 mau manawa, 10 mau manawa a me 30 mau manawa i ʻōlelo ʻia i kēlā me kēia lā no kahi pākeke 60 kg, kēlā me kēia) o ka kofe Reishi i hāʻawi waha ʻia i nā ʻiole i kēlā me kēia lā.Ma hope o 30 mau lā, ua ʻike ʻia nā hopena o ka kofe Reishi i ka hana immune o nā ʻiole e nā ʻano ʻike like ʻole.Ua ʻike ʻia:

1. Hoʻonui i ka helu splenic (helu o nā lymphocytes)

ʻO ka index splenic ka ratio o ke kaumaha o ke kino me ke kaumaha o ke kino.No ka mea, ua waiwai ka spleen i nā lymphocytes (me nā pūnaʻi B, nā pūnaewele T a me nā mea pepehi maoli).ʻO ke kiʻekiʻe o ka hoʻonui ʻana o ka lymphocyte e hoʻopili i ke kaumaha o ka spleen, a laila e ʻike ʻia i ka index splenic.No laila, hiki ke noʻonoʻo ʻia ke kūlana maʻamau o ka hana immune o ke kanaka mai ka pae o ka index.

Ua hōʻike ʻia nā hopena hoʻokolohua i hoʻohālikelike ʻia me ka pūʻulu mana i ʻai ʻoleʻO Ganoderma lucidumkope, haʻahaʻa a me waena o nāʻO Ganoderma lucidumʻAʻohe hopena koʻikoʻi o ka kofe i ka helu kiko o nā ʻiole, akā kiʻekiʻe nā kumu oʻO Ganoderma lucidumHiki i ke kofe ke hoʻonui i ka index spleen o nā ʻiole ma ka 16.7%, he mea nui loa ia.

2. ʻOi aku ka ikaika o ka hiki ʻana o nā pūnaewele T

ʻO T lymphocytes nā luna o ka ʻōnaehana pale.E hoʻoholo lākou i ke ala o ka pane ʻana i ka pale e like me ke kūlana o ka ʻenemi mai nā outposts (e like me macrophages).ʻO kekahi mau pūnaewele T e hakakā maoli i ka ʻenemi a i ʻole e hoʻomanaʻo i kēia ʻike i hiki iā lākou ke hoʻāla koke i kahi pane immune i ka manawa aʻe e hakakā ai lākou i kahi ʻenemi.No laila, ʻo ko lākou hiki ke hoʻonui i ka wā o ka "hoʻolaha" e pili ana i ka hana āpau āpau.

Wahi a nā hualoaʻa o ka ConA-induced mouse spleen lymphocyte transformation test (ʻike pū ʻia ʻo ka T cell proliferation test), ka proliferative capacity (ka ʻokoʻa OD o ka hoʻololi lymphocyte spleen) o nā lymphocytes spleen o nā ʻiole e lawe ana i ka nui a me ke kiʻekiʻe.ʻO Ganoderma lucidumkopeke hoʻoulu ʻia e ConA ua hoʻonui ʻia ma mua o 30% i hoʻohālikelike ʻia me ka pūʻulu hoʻomalu.

Ma muli o ka hoʻoulu ʻana o ConA i nā pūnaewele T, ʻo ka hoʻonui ʻana o nā lymphocytes spleen ʻiole i ʻike ʻia i loko o ka hoʻokolohua ʻo ia ka hopena o ka hoʻonui ʻana o ka cell T.

3. ʻOi aku ka ikaika o nā pūnaewele B e hana i nā antibodies a ʻoi aku ka nui o nā antibodies a lākou e hana ai.

Ua ʻike ʻia nā lymphocytes B he mau mea hana antibody.E hana lākou i nā antibodies e like me nā ʻōlelo aʻoaʻo i hoʻopuka ʻia e nā cell T e hoʻouka pololei i nā mea hoʻouka kaua i hoʻopaʻa ʻia e nā cell T.ʻO kēia "mea hoʻomaʻemaʻe kino kūikawā e hoʻohana ana i nā pūnaewele B e hana i nā antibodies e hoʻokō i ke kumu o ka pale" i kapa ʻia ʻo "humoral immunity", a ʻo ka helu o nā cell B a me ka nui o nā antibodies i hana ʻia e lilo i mau hōʻailona no ka loiloi ʻana i ka ikaika o ka palekana humoral.

Ke hālāwai nā pūnaʻi B i nā pūnaʻi koko ʻulaʻula mai nā kumu like ʻole, e hana lākou i nā antibodies e lyse i nā ʻāpana koko ʻulaʻula, a e hoʻopaʻa nā antibodies i hana ʻia i nā keʻena koko ʻulaʻula a hōʻuluʻulu i nā puʻupuʻu.Ua hoʻohana ʻia kēia waiwai no ka loiloi ʻana i ka hiki o nā ʻiole B ke hana i nā antibodies (hemolytic plaque assay) a me ka helu o nā antibodies i hana ʻia (serum hemolysin assay).

Ua ʻike ʻia kēlā kiʻekiʻe-doseʻO Ganoderma lucidumHiki i ka kofe ke hoʻomaikaʻi i ka hiki o nā pūnaʻi B ʻiole e hana i nā antibodies (ua hoʻonui ʻia ka nui o nā pā hemolytic e 23%) a me ka nui o nā antibodies i hana ʻia (ua hoʻonui ʻia ka helu o nā antibodies e 26.4%), ʻo ia ka mea a pau e kōkua i ka hoʻomaikaʻi ʻana i ka hana kūlohelohe humoral. .

4. He ikaika ka hana o na macrophages a me NK

ʻO ka palekana maikaʻi ʻaʻole wale i kahi alakaʻi alakaʻi maikaʻi (T cell) a me ke kākoʻo logistical kikoʻī (nā pūnae B a me nā antibodies) akā i kahi pūʻali kelepona hiki ke hāʻawi i ke kākoʻo mai ka ʻike ʻana i ka laina mua o ka ʻenemi i ke kaʻina hana āpau āpau.Ke pāʻani nei nā macrophages a me nā pūnaewele NK i kēlā ʻano hana.

Ma o ka "carbon clearance capacity" a me "NK cell activity assay", ua ʻike ʻia ʻo ka nui o ka nuiʻO Ganoderma lucidumkopehiki ke hoʻonui i ka mana phagocytic o macrophages e 41.7% a hoʻonui i ka hana o nā cell NK e 26.4%.He ʻokoʻa koʻikoʻi kēia i hoʻohālikelike ʻia me ka hui hoʻomalu i inu ʻoleʻO Ganoderma lucidumkope.

ʻO ka hui ʻana oGanodermalucidum a ʻoi aku ke kofe ma mua o ke kofe wale nō.

Pono ka ʻōnaehana immune i nā ʻāpana he nui e hui pū kekahi me kekahi e hana i kahi ʻupena pale paʻa.ʻO nā macrophages, nā pūnaewele NK, nā pūnaewele T, nā pūnaewele B a me nā antibodies nā kuleana koʻikoʻi i kēia pūnaewele a he mea nui ia.

Ua hōʻoia mua nā haʻawina he nui i ka wā i halaʻO Ganoderma lucidumHiki i ka extract ke hoʻoikaika i nā hopena o nā pūnaewele a me nā antibodies i ʻōlelo ʻia ma luna, a i kēia manawa ke hāʻawi nei kēia haʻawina i kumu ʻepekema no ka hana pale ʻana o "ʻO Ganoderma lucidumkofe”, he hui ia oʻO Ganoderma lucidumextract a me ke kofe.

Eia naʻe,ʻO Ganoderma lucidumʻO ke kofe ka hui ʻana o nā mea ʻelua ma hope o nā mea a pau.ʻO Ganoderma lucidumLoaʻa ka extract i nā huina palena iʻO Ganoderma lucidumkope.ʻAʻole ʻoi aku ka maikaʻi o ke kīʻaha i hoʻokahi lā a ʻelua a ʻekolu paha e like me ka hoʻohui ʻana meʻO Ganoderma lucidumwale nō, akā hiki ke hoʻonui i ka manawa.

No ka poe aloha kofe,ʻO Ganoderma lucidumkopeʻoi aku ka ʻoi aku o ka manaʻo.Ma waho aʻe o ke koʻikoʻi immune i hōʻike ʻia e nā hoʻokolohua ma luna, nā hopena oʻO Ganoderma lucidummai ka wā kahiko e "hoʻonui i ka naʻau qi" a me ka "hoʻonui i ka naʻauao a me ka hoʻomanaʻo" hiki ke pāʻani pū kekahi me ka kofe.

[Reference]

ʻO Jin Lingyun et al.Ka noiʻi ʻana e pili ana i ka hopena o ka kofe Ganoderma lucidum i ka hana immune o nā ʻiole.ʻEpekema Meaʻai a me ʻenehana, 2017, 42 (03): 83-87.

★ Ua paʻi ʻia kēia ʻatikala ma lalo o ka mana kūʻokoʻa o ka mea kākau, a no GanoHerb kona kuleana.

★ ʻAʻole hiki ke hana hou ʻia ka hana ma luna aʻe, ʻokiʻoki a hoʻohana ʻia ma nā ʻano ʻē aʻe me ka ʻole o ka ʻae ʻia e GanoHerb.

★ Inā ʻae ʻia ka hana no ka hoʻohana ʻana, pono e hoʻohana ʻia i loko o ke ʻano o ka mana a kuhikuhi i ke kumu: GanoHerb.

★ No ka uhaki ʻana i ka ʻōlelo ma luna, e ʻimi ʻo GanoHerb i nā kuleana pili kānāwai.

★ Ua kākau ʻia ka kikokikona kumu o kēia ʻatikala ma ka ʻōlelo Pākē e Wu Tingyao a unuhi ʻia i ka ʻōlelo Pelekania e Alfred Liu.Inā loaʻa kekahi ʻokoʻa ma waena o ka unuhi (English) a me ka unuhi mua (Pake), e lanakila ka Pākē mua.Inā he nīnau ka poʻe heluhelu, e ʻoluʻolu e kelepona i ka mea kākau kumu, ʻo Ms. Wu Tingyao.